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Zonisamide is a medication used to treat the symptoms of epilepsy and Parkinson's disease . [2] [3] Chemically it is a sulfonamide . It serves as an anticonvulsant used primarily as an adjunctive therapy in adults with Parkinson's disease, partial-onset seizures ; infantile spasm , mixed seizure types of Lennox–Gastaut syndrome , myoclonic and generalized tonic clonic seizure . [4] Despite this it is also sometimes used as a monotherapy for partial-onset seizures. [3] [5]

Zonisamide is used with other medications to prevent and control seizures ( epilepsy ). Zonisamide is a sulfonamide anticonvulsant and a carbonic anhydrase inhibitor. It is unknown how zonisamide works to prevent seizures.


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